The latest versions of IT Security Search include the ability to specify an AD group as the IT Search Administrators group if desired.
The config by default is located here: C:\Program Files\Quest\IT Security Search\ITSS.RestServer.exe.config
The parameter to look for is:
<add key="AdministratorGroups" value="IT Security Search Administrators" />
This "value" can be fully replaced by name of desired administrators group. For AD-based group specify the group name using domain\group format (example: contoso.com\security group name).