In this case we need to clear a few database keys and reconfigure to reset the password.
1. Firstly, change the value of below registry key.
In the following registry location erase the data for the values below, and change the last value to 0:
Location: HKLM/SOFTWARE/Quest/GPOADmin/VCConfig
Values to blank: DataSource, InitialCatalog, ServerName, UserID
Set UseSQL: 0
2. Next restart the GPOADmin services, and reconnect with the console. You will be asked to reconfigure GPOADmin allowing you to enter the database server / database / new password.