When there is a Virtual Appliance deployed for LINUX FLR purposes and it happens to reside on either the Source or Target ESX host of a COS (ESX Service Console) mode replication job you receive the above error.
The job shows transport mode of COS and checking Tools>Options>My Jobs>Protocol Failover reveals that COS mode is the only option checked.
Two possable resolutions:
1) vMotion the Virtual Appliance to a different host and refresh the vRanger Inventory
2) Refresh the vRanger inventory, remove the old replication job, create a new replication job