When attempting an ESXi replication it fails with the following:
"Error Message: 3010 - FATAL unknown_io unknown I/O method vix [at io_open_mode:92]"
A possible cause of this error is that the Virtual Appliances did not get deployed correctly and there is not correct VIX connectivity between the VA and the host that the VA resides on
Re-deploying both VA's resolved this issue
Deploy the Virtual Appliance correctly as per the vRanger Installation Guide (VA Configuration - Page 74)