PL/SQL Profiler error "The required SYS Profiler package is either missing, inaccessible or the EXECUTE privilege has not been granted"
The required privileges have been granted on SYS.DBMS_PROFILER
Uncheck option View | Toad Options | Execute/Compile | 'Use hierarchical profiler on Oracle 11g and newer'
or
'grant execute on package SYS. DBMS_HPROF to public' (or specific user) if the above remains checked.