Information on LOB replication with non-standard db_block_size.
You can have a separate tablespace with non-standard db_block_size, i.e., either 16k or 32k for LOBs (Database db_block_size = 8k)
You will need to set the chunk size of BLOB table to either 16k or 32k, i.e., same as BLOB tablespace block size.
Shareplex supports LOB replication of non-standard database block size.
The chunk size of LOB must equal to the block size of LOB tablespace and is not dependent on not db_block_size.