Disable all antivirus/scanners that are actively monitoring the host machine. If a complete disable is not possible, please strongly consider adding exceptions to the following locations:
Essentials for Office 365 installation directory. By default, this is C:\Program Files\Metalogix\Essentials or C:\Program Files (x86)\Metalogix\Essentials
Essentials for Office 365 workspace directory. By default, this is C:\Users\{UserDirectory}\Essentials
Essentials for Office 365 temporary directory. By default, this is C:\Users\{UserDirectory}\AppData\Local\Temp
Essentials for Office 365 backup location. If you are storing backups locally, please add this location(s) to the exception list as well.