SOLUTION:
Increase the total system RAM and then increase the JVM memory. (For example, increase the system RAM to 12 GB, then increase the JVM memory to 8 GB.)
How to increase JVM Memory for Spotlight:
1. Stop Diagnostic Server service.
2. Edit the 'C:\Program Files\Quest Software\Diagnostic Server\Agent\bin\SpotlightDiagnosticServer.ini' file.
3. Change the value within from "-Xmx6144m" to "-Xmx8192m", this is to increase JVM from default 6 GB to 8 GB.
4. Start Diagnostic Server service.