When trying to connect to a database an Ora-65535 error is being returned. In the Connect Using dropdown, it shows Oracle Root as the client. If the Connect Using value is changed from Oracle Root to the name of the actual Oracle client installed on the machine, then the database connects without issue. However, if a second connection is attempted, the Connect Using field has Oracle Root listed again. The second connection can be made without error.
If the databases are disconnected, so there are no more connections through Toad, when going back to the connection window, it still has Oracle Root listed in Connect Using. If a connection is attempted, the Ora-65535 error is returned again. When double clicking on the saved connection, it always has the Oracle Root saved as the client and always gives the error. User has to manually change the Connect Using value to the actual client every time to get it to connect.