A message "Information cannot be loaded through a DB link" appears when clicking on the Deps (Used By) tab in the Right-Hand-Side of the Schema Browser for any Synonym with a DB_Link. Normal synonyms are fine.
This message did not appear in Toad for Oracle 10.5 and will show object data in the Deps (Used By) tab.
The message, "Information cannot be loaded through a DB link" when clicking the "Used By" tab for objects with a DB_Link was an intentional change because the way it worked in 10.5 and prior was buggy.
Here is why: the object being shown on the Right-Hand-Side (RHS) in your screen shot example is a package. So the USED BY tab on the RHS should show the objects which use the package. Toad for Oracle 10.5 was actually showing the objects in the local database that use the synonym instead, which is not the intension to show for DB_Link objects, hence it was buggy.
Any objects in the linked database that use the package would not be shown the way they normally would if you connected to the linked database and found the package in the schema browser and then went to the 'Used By' tab. The query we use to load the 'Used By' information uses a CONNECT BY query. These types of queries cannot be performed through database links, which is why that tab does now not show any information on objects through database links.