"Oracle SID was changed from {Instance_name} to SYS$USERS on agent" messages are printed in Oracle agent log files for version 7.3.2.16 through 8.0.0.13 Oracle cartridges.
This can cause various issues including
Coding issue
Contact Support Hotfix HFIX-592 for this issue.
Status
This issue has been logged as defect HFIX-592 and will be fixed in an upcoming release of the Oracle cartridge.