The whole Data Grid interface in Toad for Oracle can be edited and customized, which also means more steps in changing just the Font in the Data Grid. It will also affects other data grids such as in the Editor window.
1) Go to View Menu | Toad Options | Data Grids | Visual | under Styles section | click on "Edit Styles" button.
2) So that the original styles are preserved, highlight "Legacy" style | then click on the "Clone" button | name it as i.e. Legacy2 | click OK.
3) Next highlight Legacy2 | click on the Edit button.
4) Under Grid Element | highlight "ContentEven" | and then click on the button right next to Font
5) Choose the font you want to use.
6) Perform steps 4 and 5 on "ContentOdd".
7) Continue to save and apply the changes you made.