When running Client Profile Updating Utility (CPUU) against a Outlook 2010 64 bit (x64) client the following error is found in the CPUU log
10/4/2017 9:16:21 AM 9268 [Info] Default mail client: Outlook64Bridge.
10/4/2017 9:16:21 AM 9268 [Info] Temporarily changing the default mail client to 'Microsoft Outlook'.
10/4/2017 9:16:21 AM 9268 [Error] Cannot set default mail client.
Standard result: 0x00000005, Description: Access is denied.
You need to be signed in and under a current maintenance contract to view premium knowledge articles.