Make sure the .NET client requirements are met .These requirements can be found here:
https://support.quest.com/technical-documents/spotlight-on-sql-server-enterprise/11.6/release-notes/release-notes/system-requirements
Check also the Windows Event Viewer in the computer where the Spotlight client is crashing.
In this case Windows was complaining about Framework version: v4.0.30319.
After removing this NET version everything was fine.
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