Logon Error -2147221231 The information store could not be opened. - MAPI_E_LOGON_FAILED (4222280)

1. In the console tree, navigate to Recipient Configuration>Mailbox.
2. In the result pane, select the user mailbox for which you want to enable or disable MAPI.
3. In the action pane, under the user mailbox name, clickProperties.
4. In< User Mailbox > Properties, on the Mailbox Features tab, click MAPI, and then click either Enable or Disable.
5. Click OK.

You need to be assigned permissions before you can perform this procedure. To see what permissions you need, see the "Client Access user settings" entry in the Client Access Permissions topic.

This example enables MAPI for the user John.

Set-CASMailbox -Identity John -MAPIEnabled $true

This example disables MAPI for the user John.

Set-CASMailbox -Identity John -MAPIEnabled $false

For detailed syntax and parameter information, see Set-CASMailbox.