From FMS logs:
com.quest.nitro.service.agent.AgentManager - Canonical data transform failed. Some agent data may be lost: java.lang.IllegalStateException: Error processing incoming data for root node: JavaEE-Cartridge::Java_EE-5_7_0/cdt-5_7_0/common/cdt/javaee.xml: com.quest.nitro.service.sl.interfaces.topology.TopologyChangeVetoException: The configured limit of 10000 instances of type JavaEERequestClass has been reached
The limit has been reached for JavaEERequestClass which is for object tracking statistics.
Usually object tracking should not be enabled for a longer period of time, say only few hours. Also you might want to enable it only for a set of requests rather than all the requests
Please delete the above topologies using the below KB