It is currently not possible to switch an integration from one Nexus Connections set to another. The only way to change which Nexus an agent connects to is to edit the existing Nexus Connections set that its integration was originally configured with, change the hostname and then update ALL agents which were integrated with that Nexus Connections set.
I expected to be able to define a new Nexus Connections set and then switch the integration to use it.
CAC-344 has been filed to add an option to allow switching a Nexus Connection for exisiting integration
STATUS:Fixed in 5.9.4 release